Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0012700 Intron-Exon-Intron chr2:171911593-171948777 chr2:171055083-171092267 250 nt 0.3040
hsa_TLK1_0013200 Exon-Exon chr2:171912981-171917666 chr2:171056471-171061156 76 nt 0.4342
hsa_TLK1_0013300 Exon-Exon chr2:171912981-171939362 chr2:171056471-171082852 168 nt 0.4345
hsa_TLK1_0013100 Intron-Exon-Intron chr2:171912981-171948737 chr2:171056471-171092227 250 nt 0.3480
hsa_TLK1_0013400 Exon-Exon chr2:171912981-171974367 chr2:171056471-171117857 119 nt 0.4706
hsa_TLK1_0013500 Exon-Exon chr2:171914661-171974367 chr2:171058151-171117857 377 nt 0.4589
hsa_TLK1_0013800 Intron-Exon-Intron chr2:171917591-171948737 chr2:171061081-171092227 148 nt 0.4122
hsa_TLK1_0013700 Intron-Exon-Intron chr2:171917591-171948777 chr2:171061081-171092267 250 nt 0.3040
hsa_TLK1_0013900 Exon-Exon chr2:171917591-171974367 chr2:171061081-171117857 119 nt 0.4706
hsa_TLK1_0014000 Exon-Exon chr2:171917591-172016949 chr2:171061081-171160439 76 nt 0.4342
Showing 181 to 190 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].