Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0014100 Exon-Intron chr2:171917600-171938149 chr2:171061090-171081639 250 nt 0.2720
hsa_chr2_0269000 Intergenic-Intergenic chr2:171918540-171918872 chr2:171062030-171062362 333 nt 0.3694
hsa_TLK1_0014200 Intron-Intron chr2:171923975-171933149 chr2:171067465-171076639 250 nt 0.2960
hsa_TLK1_0014500 Intron-Exon-Intron chr2:171938150-171948737 chr2:171081640-171092227 335 nt 0.4627
hsa_TLK1_0014600 Intron-Exon-Intron chr2:171938150-171963648 chr2:171081640-171107138 152 nt 0.4737
hsa_TLK1_0015000 Intron-Exon-Intron chr2:171939291-171948737 chr2:171082781-171092227 335 nt 0.4627
hsa_TLK1_0015100 Intron-Exon-Intron chr2:171939291-171948777 chr2:171082781-171092267 72 nt 0.3889
hsa_TLK1_0015200 Intron-Exon-Intron chr2:171939291-171963648 chr2:171082781-171107138 83 nt 0.4458
hsa_TLK1_0015300 Intron-Exon-Intron chr2:171939291-172008292 chr2:171082781-171151782 335 nt 0.4627
hsa_TLK1_0015400 Intron-Exon-Intron chr2:171939291-172010037 chr2:171082781-171153527 163 nt 0.3926
Showing 191 to 200 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].