Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0014900 Intron-Exon-Intron chr2:171939291-172048144 chr2:171082781-171191634 250 nt 0.3760
hsa_chr2_0269100 Intergenic-Intergenic chr2:171944746-171945518 chr2:171088236-171089008 773 nt 0.4036
hsa_chr2_0269200 Intergenic-Intergenic chr2:171945721-171950528 chr2:171089211-171094018 146 nt 0.3493
hsa_TLK1_0015500 Intron-Intron chr2:171947735-171948094 chr2:171091225-171091584 360 nt 0.3667
hsa_TLK1_0015600 Intron-Intron chr2:171948124-171948737 chr2:171091614-171092227 614 nt 0.4853
hsa_TLK1_0015700 Intron-Exon-Intron chr2:171948124-171974367 chr2:171091614-171117857 119 nt 0.4706
hsa_TLK1_0015800 Intron-Exon-Intron chr2:171963566-171974367 chr2:171107056-171117857 202 nt 0.4604
hsa_TLK1_0015900 Intron-Intron chr2:171971171-171971931 chr2:171114661-171115421 761 nt 0.4284
hsa_TLK1_0016400 Intron-Exon-Intron chr2:171974249-171988602 chr2:171117739-171132092 250 nt 0.3360
hsa_TLK1_0016500 Intron-Exon-Intron chr2:171974249-171990914 chr2:171117739-171134404 176 nt 0.3920
Showing 201 to 210 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].