Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0016600 Intron-Exon-Intron chr2:171974249-172010037 chr2:171117739-171153527 210 nt 0.4381
hsa_TLK1_0016700 Intron-Exon-Intron chr2:171974249-172012543 chr2:171117739-171156033 193 nt 0.4611
hsa_TLK1_0016800 Intron-Exon-Intron chr2:171974249-172023319 chr2:171117739-171166809 226 nt 0.4602
hsa_TLK1_0016900 Intron-Exon-Intron chr2:171974249-172037835 chr2:171117739-171181325 95 nt 0.3579
hsa_TLK1_0017000 Intron-Intron chr2:171979472-171979788 chr2:171122962-171123278 317 nt 0.3975
hsa_TLK1_0017100 Intron-Intron chr2:171979511-171979788 chr2:171123001-171123278 278 nt 0.3705
hsa_TLK1_0017200 Intron-Intron chr2:172006708-172006942 chr2:171150198-171150432 235 nt 0.3064
hsa_TLK1_0017300 Intron-Intron chr2:172009947-172012759 chr2:171153437-171156249 267 nt 0.4007
hsa_TLK1_0017400 Intron-Intron chr2:172081499-172082012 chr2:171224989-171225502 514 nt 0.3482
hsa_chr2_0268200 Intergenic-Intergenic chr2:171847445-171847590 chr2:170990935-170991080 146 nt 0.3082
Showing 211 to 220 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].