Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0001200 Intron-Exon-Intron chr2:171853776-171854882 chr2:170997266-170998372 1107 nt 0.3595
hsa_TLK1_0001300 Exon-Exon chr2:171854222-171863153 chr2:170997712-171006643 418 nt 0.3947
hsa_TLK1_0001400 Exon-Exon chr2:171854222-171867964 chr2:170997712-171011454 112 nt 0.4018
hsa_TLK1_0001500 Intron-Exon-Intron chr2:171854222-171879507 chr2:170997712-171022997 132 nt 0.4394
hsa_TLK1_0001600 Exon-Exon chr2:171854222-171884915 chr2:170997712-171028405 67 nt 0.3433
hsa_TLK1_0001700 Exon-Exon chr2:171854222-171902872 chr2:170997712-171046362 1294 nt 0.3934
hsa_TLK1_0001800 Exon-Exon chr2:171854222-171939362 chr2:170997712-171082852 78 nt 0.3846
hsa_TLK1_0001900 Intron-Intron chr2:171856812-171858400 chr2:171000302-171001890 1589 nt 0.4103
hsa_chr2_0268400 Intergenic-Intergenic chr2:171858551-171859569 chr2:171002041-171003059 1019 nt 0.4897
hsa_TLK1_0002500 Exon-Exon chr2:171862657-171863399 chr2:171006147-171006889 90 nt 0.3778
Showing 231 to 240 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].