Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0002400 Exon-Exon chr2:171862657-171871454 chr2:171006147-171014944 664 nt 0.3765
hsa_TLK1_0002600 Exon-Exon chr2:171862657-171871458 chr2:171006147-171014948 142 nt 0.4366
hsa_TLK1_0002300 Intron-Exon-Intron chr2:171862657-171873227 chr2:171006147-171016717 2437 nt 0.3874
hsa_TLK1_0002700 Intron-Exon-Intron chr2:171862657-171879507 chr2:171006147-171022997 136 nt 0.4338
hsa_TLK1_0002800 Intron-Exon-Intron chr2:171862657-171879639 chr2:171006147-171023129 926 nt 0.3920
hsa_TLK1_0002900 Exon-Exon chr2:171862657-171884915 chr2:171006147-171028405 203 nt 0.4039
hsa_TLK1_0003000 Exon-Exon chr2:171862657-171906684 chr2:171006147-171050174 136 nt 0.4338
hsa_TLK1_0003200 Exon-Exon chr2:171862657-171939362 chr2:171006147-171082852 148 nt 0.4122
hsa_chr2_0268500 Intergenic-Intergenic chr2:171862660-171917662 chr2:171006150-171061152 1630 nt 0.3975
hsa_TLK1_0003400 Exon-Exon chr2:171862984-171871458 chr2:171006474-171014948 268 nt 0.3657
Showing 241 to 250 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].