Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0003500 Exon-Exon chr2:171862984-171902872 chr2:171006474-171046362 1046 nt 0.3872
hsa_TLK1_0003600 Exon-Exon chr2:171863310-171863573 chr2:171006800-171007063 182 nt 0.3681
hsa_TLK1_0003700 Exon-Exon chr2:171863310-171871458 chr2:171006800-171014948 98 nt 0.3776
hsa_TLK1_0003800 Exon-Exon chr2:171863310-171902872 chr2:171006800-171046362 90 nt 0.3778
hsa_TLK1_0003900 Exon-Exon chr2:171863310-171910363 chr2:171006800-171053853 99 nt 0.3939
hsa_TLK1_0004100 Exon-Exon chr2:171863482-171884915 chr2:171006972-171028405 597 nt 0.3886
hsa_chr2_0268600 Intergenic-Intergenic chr2:171867387-171867806 chr2:171010877-171011296 420 nt 0.4643
hsa_TLK1_0004500 Exon-Exon chr2:171867883-171871454 chr2:171011373-171014944 176 nt 0.3580
hsa_TLK1_0004600 Intron-Exon-Intron chr2:171867883-171879507 chr2:171011373-171022997 224 nt 0.4152
hsa_TLK1_0004700 Intron-Exon-Intron chr2:171867883-171879639 chr2:171011373-171023129 180 nt 0.3611
Showing 251 to 260 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].