Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0005900 Intron-Exon-Intron chr2:171871361-171922529 chr2:171014851-171066019 98 nt 0.3776
hsa_TLK1_0006000 Exon-Exon chr2:171871361-171939362 chr2:171014851-171082852 98 nt 0.3776
hsa_TLK1_0006100 Exon-Exon chr2:171871361-171974367 chr2:171014851-171117857 244 nt 0.4180
hsa_TLK1_0006200 Intron-Intron chr2:171872511-171872758 chr2:171016001-171016248 248 nt 0.5323
hsa_TLK1_0006300 Intron-Intron chr2:171872511-171872761 chr2:171016001-171016251 251 nt 0.5339
hsa_TLK1_0006400 Intron-Intron chr2:171872991-171873131 chr2:171016481-171016621 141 nt 0.2837
hsa_TLK1_0006500 Intron-Intron chr2:171877843-171878659 chr2:171021333-171022149 817 nt 0.4553
hsa_TLK1_0006900 Intron-Intron chr2:171879382-171881302 chr2:171022872-171024792 1921 nt 0.3358
hsa_TLK1_0007000 Intron-Exon-Intron chr2:171879382-171906684 chr2:171022872-171050174 237 nt 0.3797
hsa_TLK1_0007100 Intron-Exon-Intron chr2:171879382-171917666 chr2:171022872-171061156 76 nt 0.4342
Showing 271 to 280 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].