Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0007200 Intron-Exon chr2:171879382-171939330 chr2:171022872-171082820 166 nt 0.4277
hsa_TLK1_0007300 Intron-Exon-Intron chr2:171879382-171939362 chr2:171022872-171082852 72 nt 0.3889
hsa_TLK1_0007500 Intron-Intron chr2:171879508-171881302 chr2:171022998-171024792 1795 nt 0.3281
hsa_TLK1_0007600 Intron-Exon-Intron chr2:171879508-171902872 chr2:171022998-171046362 132 nt 0.4167
hsa_TLK1_0007700 Intron-Exon-Intron chr2:171881211-171884915 chr2:171024701-171028405 250 nt 0.2640
hsa_TLK1_0007900 Intron-Exon-Intron chr2:171883262-171884915 chr2:171026752-171028405 1654 nt 0.3313
hsa_TLK1_0007800 Intron-Exon-Intron chr2:171883262-171939362 chr2:171026752-171082852 2628 nt 0.3626
hsa_TLK1_0008000 Intron-Exon-Intron chr2:171883694-171884915 chr2:171027184-171028405 146 nt 0.3699
hsa_TLK1_0008800 Exon-Exon chr2:171884849-171906450 chr2:171028339-171049940 383 nt 0.4021
hsa_TLK1_0008900 Exon-Exon chr2:171884849-171906460 chr2:171028339-171049950 393 nt 0.4020
Showing 281 to 290 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].