Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0009600 Intron-Exon-Intron chr2:171901572-171906684 chr2:171045062-171050174 111 nt 0.3063
hsa_TLK1_0010200 Exon-Exon chr2:171902684-171902872 chr2:171046174-171046362 189 nt 0.4127
hsa_TLK1_0010400 Exon-Exon chr2:171902684-171911682 chr2:171046174-171055172 90 nt 0.4111
hsa_TLK1_0010300 Exon-Exon chr2:171902684-171913076 chr2:171046174-171056566 716 nt 0.4022
hsa_TLK1_0010500 Exon-Exon chr2:171902684-171917666 chr2:171046174-171061156 265 nt 0.4189
hsa_TLK1_0009900 Intron-Exon-Intron chr2:171902684-171922491 chr2:171046174-171065981 250 nt 0.3000
hsa_TLK1_0010600 Exon-Exon chr2:171902684-171939330 chr2:171046174-171082820 40 nt 0.3750
hsa_TLK1_0010700 Exon-Exon chr2:171902684-171939362 chr2:171046174-171082852 78 nt 0.3846
hsa_TLK1_0010800 Intron-Exon-Intron chr2:171902684-171948737 chr2:171046174-171092227 189 nt 0.4127
hsa_TLK1_0010000 Intron-Exon-Intron chr2:171902684-171948777 chr2:171046174-171092267 250 nt 0.3040
Showing 301 to 310 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].