Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0004200 Exon-Exon chr2:171867883-171871458 chr2:171011373-171014948 180 nt 0.3611
hsa_TLK1_0004300 Exon-Exon chr2:171867883-171884915 chr2:171011373-171028405 247 nt 0.3563
hsa_TLK1_0004400 Exon-Exon chr2:171867883-171906684 chr2:171011373-171050174 684 nt 0.3757
hsa_TLK1_0005300 Exon-Exon chr2:171871361-171884915 chr2:171014851-171028405 165 nt 0.3636
hsa_TLK1_0006600 Intron-Intron chr2:171879382-171879639 chr2:171022872-171023129 258 nt 0.4302
hsa_TLK1_0006700 Intron-Exon-Intron chr2:171879382-171884915 chr2:171022872-171028405 250 nt 0.3160
hsa_TLK1_0006800 Intron-Exon-Intron chr2:171879382-171902872 chr2:171022872-171046362 250 nt 0.3640
hsa_TLK1_0007400 Intron-Exon-Intron chr2:171879382-171974367 chr2:171022872-171117857 250 nt 0.3760
hsa_TLK1_0008100 Exon-Exon chr2:171884849-171884915 chr2:171028339-171028405 67 nt 0.3433
hsa_TLK1_0008200 Exon-Exon chr2:171884849-171902872 chr2:171028339-171046362 256 nt 0.3945
Showing 41 to 50 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].