Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0008300 Exon-Exon chr2:171884849-171914707 chr2:171028339-171058197 830 nt 0.3976
hsa_TLK1_0008400 Exon-Exon chr2:171884849-172087824 chr2:171028339-171231314 1267 nt 0.4238
hsa_TLK1_0009700 Exon-Exon chr2:171902684-171906684 chr2:171046174-171050174 437 nt 0.3867
hsa_TLK1_0009800 Exon-Exon chr2:171902684-171914707 chr2:171046174-171058197 763 nt 0.4024
hsa_TLK1_0012400 Exon-Exon chr2:171910271-171917666 chr2:171053761-171061156 402 nt 0.4254
hsa_TLK1_0013600 Exon-Exon chr2:171914661-171939362 chr2:171058151-171082852 195 nt 0.4103
hsa_TLK1_0014300 Intron-Exon-Intron chr2:171938150-171939362 chr2:171081640-171082852 1213 nt 0.3677
hsa_TLK1_0014400 Intron-Exon-Intron chr2:171938150-171974367 chr2:171081640-171117857 1332 nt 0.3769
hsa_TLK1_0014700 Exon-Exon chr2:171939291-171974367 chr2:171082781-171117857 191 nt 0.4398
hsa_TLK1_0014800 Exon-Exon chr2:171939291-172017410 chr2:171082781-171160900 802 nt 0.6534
Showing 51 to 60 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].