Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0016000 Intron-Exon-Intron chr2:171972125-171974367 chr2:171115615-171117857 2243 nt 0.3812
hsa_TLK1_0016100 Intron-Exon-Intron chr2:171973828-171974367 chr2:171117318-171117857 540 nt 0.3926
hsa_TLK1_0016200 Exon-Exon chr2:171974249-171974367 chr2:171117739-171117857 119 nt 0.4706
hsa_TLK1_0016300 Exon-Exon chr2:171974249-172017410 chr2:171117739-171160900 730 nt 0.6795
hsa_snoU13_0002500 Intergenic-Exon-Intergenic chr2:171993696-172013507 chr2:171137186-171156997 250 nt 0.4160
hsa_snoU13_0002500 Intergenic-Exon-Intergenic chr2:171993696-172013507 chr2:171137186-171156997 250 nt 0.4160
hsa_chr2_0268200 Intergenic-Intergenic chr2:171847445-171847590 chr2:170990935-170991080 146 nt 0.3082
hsa_TLK1_0000200 Exon-Exon chr2:171849519-171850028 chr2:170993009-170993518 510 nt 0.3176
hsa_chr2_0268300 Intergenic-Intergenic chr2:171850240-171850391 chr2:170993730-170993881 152 nt 0.4408
hsa_TLK1_0000300 Exon-Exon chr2:171853163-171863153 chr2:170996653-171006643 108 nt 0.3889
Showing 61 to 70 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].