Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0000400 Exon-Exon chr2:171853163-171863399 chr2:170996653-171006889 90 nt 0.3778
hsa_TLK1_0000500 Exon-Exon chr2:171853163-171871458 chr2:170996653-171014948 318 nt 0.3899
hsa_TLK1_0000600 Intron-Exon-Intron chr2:171853163-171879507 chr2:170996653-171022997 1014 nt 0.3895
hsa_TLK1_0000700 Intron-Exon-Intron chr2:171853163-171879639 chr2:170996653-171023129 258 nt 0.4302
hsa_TLK1_0000800 Exon-Exon chr2:171853163-171884915 chr2:170996653-171028405 1213 nt 0.3899
hsa_TLK1_0000900 Exon-Exon chr2:171853163-171906684 chr2:170996653-171050174 1650 nt 0.3891
hsa_TLK1_0001100 Exon-Exon chr2:171853163-171939362 chr2:170996653-171082852 180 nt 0.3889
hsa_TLK1_0001200 Intron-Exon-Intron chr2:171853776-171854882 chr2:170997266-170998372 1107 nt 0.3595
hsa_TLK1_0001300 Exon-Exon chr2:171854222-171863153 chr2:170997712-171006643 418 nt 0.3947
hsa_TLK1_0001400 Exon-Exon chr2:171854222-171867964 chr2:170997712-171011454 112 nt 0.4018
Showing 71 to 80 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].