Basic Information

Symbol
circTLK1
RNA Class
circRNA
Alias
Tousled Like Kinase 1 KIAA0137 PKU-BETA Serine/Threonine-Protein Kinase Tousled-Like 1 Tousled-Like Kinase 1 EC 2.7.11.1 Serine Threonine Protein Kinase SNARE Protein Kinase SNAK EC 2.7.11 PKU-Beta
Location (GRCh37)
2:171847333-172087824 UCSC Genome Browser
Location (GRCh38)
2:170990823-171231314
UCSC Genome Browser Search in Marker Scope
Host gene
TLK1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden death from CNS diseases
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TLK1_0001500 Intron-Exon-Intron chr2:171854222-171879507 chr2:170997712-171022997 132 nt 0.4394
hsa_TLK1_0001600 Exon-Exon chr2:171854222-171884915 chr2:170997712-171028405 67 nt 0.3433
hsa_TLK1_0001700 Exon-Exon chr2:171854222-171902872 chr2:170997712-171046362 1294 nt 0.3934
hsa_TLK1_0001800 Exon-Exon chr2:171854222-171939362 chr2:170997712-171082852 78 nt 0.3846
hsa_TLK1_0001900 Intron-Intron chr2:171856812-171858400 chr2:171000302-171001890 1589 nt 0.4103
hsa_chr2_0268400 Intergenic-Intergenic chr2:171858551-171859569 chr2:171002041-171003059 1019 nt 0.4897
hsa_TLK1_0002500 Exon-Exon chr2:171862657-171863399 chr2:171006147-171006889 90 nt 0.3778
hsa_TLK1_0002400 Exon-Exon chr2:171862657-171871454 chr2:171006147-171014944 664 nt 0.3765
hsa_TLK1_0002600 Exon-Exon chr2:171862657-171871458 chr2:171006147-171014948 142 nt 0.4366
hsa_TLK1_0002300 Intron-Exon-Intron chr2:171862657-171873227 chr2:171006147-171016717 2437 nt 0.3874
Showing 81 to 90 of 372 entries
Forensic Context

A study in mice demonstrated that the circTLK1 is increased after stroke, where it functions as a miR-335-3p sponge to derepress TIPARP, thereby worsening ischemic injury [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746]. A study in humans identified the circTLK1 as a circRNA involved in the septic acute kidney injury (SAKI) process [Ma et al. DOI:10.3389/fgene.2023.1209042].