Basic Information

Symbol
circTMEM165
RNA Class
circRNA
Alias
Transmembrane Protein 165 TPARL SLC64A1 TMPT27 GDT1 Putative Divalent Cation/Proton Antiporter TMEM165 Transmembrane Protein TPARL Transmembrane Protein PT27 TPA Regulated Locus CDG2K FT27
Location (GRCh37)
4:56225513-56310050 UCSC Genome Browser
Location (GRCh38)
4:55359346-55443883
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM165
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TMEM165_0000700 Intron-Exon-Intron chr4:56265253-56278006 chr4:55399086-55411839 226 nt 0.4204
hsa_TMEM165_0000800 Intron-Exon-Intron chr4:56265253-56284152 chr4:55399086-55417985 286 nt 0.3846
hsa_TMEM165_0000900 Intron-Exon chr4:56265253-56291655 chr4:55399086-55425488 113 nt 0.3274
hsa_TMEM165_0001000 Intron-Exon-Intron chr4:56265267-56269505 chr4:55399100-55403338 250 nt 0.3040
hsa_TMEM165_0001200 Intron-Exon-Intron chr4:56265267-56284152 chr4:55399100-55417985 337 nt 0.3976
hsa_TMEM165_0001100 Intron-Exon-Intron chr4:56265267-56284331 chr4:55399100-55418164 250 nt 0.3400
hsa_TMEM165_0001300 Intron-Intron chr4:56265277-56265420 chr4:55399110-55399253 144 nt 0.4167
hsa_TMEM165_0001400 Intron-Exon-Intron chr4:56265913-56269505 chr4:55399746-55403338 250 nt 0.3640
hsa_chr4_0486300 Intergenic-Intergenic chr4:56266892-56267287 chr4:55400725-55401120 396 nt 0.3611
hsa_TMEM165_0001500 Intron-Exon-Intron chr4:56267820-56269505 chr4:55401653-55403338 1686 nt 0.4187
Showing 21 to 30 of 57 entries
Forensic Context

A study in humans demonstrated that the circTMEM165 (hsa_circ_0001414) was significantly upregulated in the peripheral blood of myocardial infarction patients compared to healthy controls, as identified by RNA sequencing and validated by RT-qPCR [Li et al. DOI:10.3389/fcvm.2022.810257]. A study in human patients with ST-segment elevation myocardial infarction (STEMI) identified the circTMEM165 as a differentially expressed circular RNA in peripheral blood, a finding that was confirmed in an AC16 cell model [Wang et al. DOI:10.1515/med-2023-0807].