Basic Information

Symbol
circTMEM165
RNA Class
circRNA
Alias
Transmembrane Protein 165 TPARL SLC64A1 TMPT27 GDT1 Putative Divalent Cation/Proton Antiporter TMEM165 Transmembrane Protein TPARL Transmembrane Protein PT27 TPA Regulated Locus CDG2K FT27
Location (GRCh37)
4:56225513-56310050 UCSC Genome Browser
Location (GRCh38)
4:55359346-55443883
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM165
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TMEM165_0002700 Intron-Exon-Intron chr4:56275112-56284152 chr4:55408945-55417985 152 nt 0.3947
hsa_TMEM165_0002800 Intron-Intergenic chr4:56275112-56295232 chr4:55408945-55429065 171 nt 0.4620
hsa_TMEM165_0003500 Exon-Exon chr4:56277781-56284134 chr4:55411614-55417967 165 nt 0.3758
hsa_TMEM165_0003600 Exon-Exon chr4:56277781-56291655 chr4:55411614-55425488 339 nt 0.3894
hsa_TMEM165_0003400 Exon-Intergenic chr4:56277781-56295232 chr4:55411614-55429065 250 nt 0.2680
hsa_TMEM165_0003700 Intron-Intron chr4:56278362-56279684 chr4:55412195-55413517 1323 nt 0.3764
hsa_TMEM165_0003800 Intron-Exon-Intron chr4:56282209-56284152 chr4:55416042-55417985 50 nt 0.4400
hsa_TMEM165_0003900 Intron-Exon-Intron chr4:56282209-56284331 chr4:55416042-55418164 654 nt 0.4297
hsa_TMEM165_0004000 Intron-Exon chr4:56283154-56291655 chr4:55416987-55425488 113 nt 0.3274
hsa_TMEM165_0004300 Intron-Exon-Intron chr4:56283239-56284331 chr4:55417072-55418164 339 nt 0.4218
Showing 41 to 50 of 57 entries
Forensic Context

A study in humans demonstrated that the circTMEM165 (hsa_circ_0001414) was significantly upregulated in the peripheral blood of myocardial infarction patients compared to healthy controls, as identified by RNA sequencing and validated by RT-qPCR [Li et al. DOI:10.3389/fcvm.2022.810257]. A study in human patients with ST-segment elevation myocardial infarction (STEMI) identified the circTMEM165 as a differentially expressed circular RNA in peripheral blood, a finding that was confirmed in an AC16 cell model [Wang et al. DOI:10.1515/med-2023-0807].