Basic Information
Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough
TMEM56-RWDD3 Readthrough
TMEM56-RWDD3
TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550
UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RP11-57H12.6_0001300 | Intron-Exon-Intron | chr1:95603831-95616975 | chr1:95138275-95151419 | 250 nt | 0.3400 |
| hsa_RP11-57H12.6_0001500 | Intron-Exon-Intron | chr1:95603831-95639445 | chr1:95138275-95173889 | 250 nt | 0.3840 |
| hsa_RP11-57H12.6_0003600 | Exon-Exon | chr1:95609447-95639445 | chr1:95143891-95173889 | 484 nt | 0.3967 |
| hsa_RP11-57H12.6_0003700 | Intron-Exon-Intron | chr1:95609447-95644494 | chr1:95143891-95178938 | 250 nt | 0.3280 |
| hsa_RP11-57H12.6_0003800 | Exon-Exon | chr1:95609447-95696550 | chr1:95143891-95230994 | 577 nt | 0.4142 |
| hsa_RP11-57H12.6_0006500 | Exon-Exon | chr1:95616881-95616975 | chr1:95151325-95151419 | 95 nt | 0.3263 |
| hsa_RP11-57H12.6_0001300 | Intron-Exon-Intron | chr1:95603831-95616975 | chr1:95138275-95151419 | 250 nt | 0.3400 |
| hsa_RP11-57H12.6_0001500 | Intron-Exon-Intron | chr1:95603831-95639445 | chr1:95138275-95173889 | 250 nt | 0.3840 |
| hsa_RP11-57H12.6_0003600 | Exon-Exon | chr1:95609447-95639445 | chr1:95143891-95173889 | 484 nt | 0.3967 |
| hsa_RP11-57H12.6_0003700 | Intron-Exon-Intron | chr1:95609447-95644494 | chr1:95143891-95178938 | 250 nt | 0.3280 |
Showing 1 to 10 of 166 entries
Forensic Context
A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].