Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0000500 Intron-Exon-Intron chr1:95600338-95618108 chr1:95134782-95152552 443 nt 0.3860
hsa_RP11-57H12.6_0000600 Intron-Exon-Intron chr1:95600507-95616975 chr1:95134951-95151419 345 nt 0.3739
hsa_RP11-57H12.6_0000700 Intron-Exon-Intron chr1:95602249-95616975 chr1:95136693-95151419 557 nt 0.4183
hsa_RP11-57H12.6_0000800 Intron-Exon-Intron chr1:95602249-95618136 chr1:95136693-95152580 84 nt 0.2976
hsa_RP11-57H12.6_0001200 Intron-Exon chr1:95603831-95609532 chr1:95138275-95143976 86 nt 0.3605
hsa_RP11-57H12.6_0001400 Intron-Exon-Intron chr1:95603831-95618158 chr1:95138275-95152602 106 nt 0.2925
hsa_RP11-57H12.6_0000900 Intron-Exon-Intron chr1:95603831-95626705 chr1:95138275-95161149 250 nt 0.3880
hsa_RP11-57H12.6_0001600 Intron-Exon-Intron chr1:95603831-95644494 chr1:95138275-95178938 43 nt 0.5581
hsa_RP11-57H12.6_0001000 Intron-Exon-Intron chr1:95603831-95647030 chr1:95138275-95181474 250 nt 0.3160
hsa_RP11-57H12.6_0001900 Intron-Exon-Intron chr1:95603836-95616975 chr1:95138280-95151419 101 nt 0.3465
Showing 91 to 100 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].