Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0003000 Intron-Exon-Intron chr1:95606229-95618136 chr1:95140673-95152580 474 nt 0.3734
hsa_RP11-57H12.6_0003100 Intron-Exon-Intron chr1:95606229-95639445 chr1:95140673-95173889 455 nt 0.4088
hsa_RP11-57H12.6_0003300 Intron-Exon-Intron chr1:95608312-95610341 chr1:95142756-95144785 2030 nt 0.3424
hsa_RP11-57H12.6_0003400 Intron-Exon-Intron chr1:95609428-95616975 chr1:95143872-95151419 95 nt 0.3263
hsa_RP11-57H12.6_0004300 Exon-Exon chr1:95609447-95614285 chr1:95143891-95148729 194 nt 0.3763
hsa_RP11-57H12.6_0004600 Intron-Exon-Intron chr1:95609447-95617036 chr1:95143891-95151480 166 nt 0.3614
hsa_RP11-57H12.6_0004700 Intron-Exon-Intron chr1:95609447-95617607 chr1:95143891-95152051 59 nt 0.4746
hsa_RP11-57H12.6_0004800 Intron-Exon-Intron chr1:95609447-95618136 chr1:95143891-95152580 414 nt 0.3671
hsa_RP11-57H12.6_0004900 Intron-Exon-Intron chr1:95609447-95618158 chr1:95143891-95152602 536 nt 0.3582
hsa_RP11-57H12.6_0003900 Intron-Exon-Intron chr1:95609447-95618729 chr1:95143891-95153173 2164 nt 0.3272
Showing 111 to 120 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].