Basic Information
Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough
TMEM56-RWDD3 Readthrough
TMEM56-RWDD3
TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550
UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RP11-57H12.6_0005000 | Intron-Exon-Intron | chr1:95609447-95618847 | chr1:95143891-95153291 | 385 nt | 0.3870 |
| hsa_RP11-57H12.6_0004000 | Intron-Exon-Intron | chr1:95609447-95621167 | chr1:95143891-95155611 | 250 nt | 0.2840 |
| hsa_RP11-57H12.6_0005100 | Intron-Exon-Intron | chr1:95609447-95626705 | chr1:95143891-95161149 | 423 nt | 0.3806 |
| hsa_RP11-57H12.6_0005200 | Intron-Exon-Intron | chr1:95609447-95647030 | chr1:95143891-95181474 | 169 nt | 0.3964 |
| hsa_RP11-57H12.6_0005700 | Exon-Exon | chr1:95609487-95639445 | chr1:95143931-95173889 | 133 nt | 0.4812 |
| hsa_RP11-57H12.6_0005800 | Exon-Exon | chr1:95609502-95616975 | chr1:95143946-95151419 | 206 nt | 0.3398 |
| hsa_RP11-57H12.6_0005900 | Exon-Exon | chr1:95609502-95639445 | chr1:95143946-95173889 | 111 nt | 0.3514 |
| hsa_RP11-57H12.6_0006000 | Exon-Exon | chr1:95609518-95616975 | chr1:95143962-95151419 | 154 nt | 0.3831 |
| hsa_RP11-57H12.6_0006100 | Exon-Exon | chr1:95609538-95616975 | chr1:95143982-95151419 | 170 nt | 0.3412 |
| hsa_RP11-57H12.6_0006200 | Intron-Exon-Intron | chr1:95614258-95626705 | chr1:95148702-95161149 | 250 nt | 0.3560 |
Showing 121 to 130 of 166 entries
Forensic Context
A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].