Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0006600 Intron-Intron chr1:95631643-95632211 chr1:95166087-95166655 569 nt 0.3937
hsa_RP11-57H12.6_0006700 Intron-Exon-Intron chr1:95639372-95644494 chr1:95173816-95178938 74 nt 0.4865
hsa_Y_RNA_0010000 Intergenic-Exon-Intergenic chr1:95583013-95603944 chr1:95117457-95138388 161 nt 0.7826
hsa_Y_RNA_0010000 Intergenic-Exon-Intergenic chr1:95583013-95603944 chr1:95117457-95138388 161 nt 0.7826
hsa_TMEM56_0000400 Intron-Exon-Intron chr1:95586611-95602346 chr1:95121055-95136790 104 nt 0.4231
hsa_TMEM56_0000500 Exon-Exon chr1:95586611-95616975 chr1:95121055-95151419 284 nt 0.3979
hsa_TMEM56_0000300 Intron-Exon-Intron chr1:95586611-95626705 chr1:95121055-95161149 250 nt 0.3440
hsa_chr1_1154500 Intergenic-Intergenic chr1:95588664-95588976 chr1:95123108-95123420 313 nt 0.3770
hsa_TMEM56_0000600 Intron-Exon chr1:95603831-95657237 chr1:95138275-95191681 132 nt 0.4015
hsa_TMEM56_0000700 Intron-Exon chr1:95606229-95657237 chr1:95140673-95191681 165 nt 0.3879
Showing 131 to 140 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].