Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TMEM56_0000400 Intron-Exon-Intron chr1:95586611-95602346 chr1:95121055-95136790 104 nt 0.4231
hsa_TMEM56_0000500 Exon-Exon chr1:95586611-95616975 chr1:95121055-95151419 284 nt 0.3979
hsa_TMEM56_0000300 Intron-Exon-Intron chr1:95586611-95626705 chr1:95121055-95161149 250 nt 0.3440
hsa_chr1_1154500 Intergenic-Intergenic chr1:95588664-95588976 chr1:95123108-95123420 313 nt 0.3770
hsa_TMEM56_0000600 Intron-Exon chr1:95603831-95657237 chr1:95138275-95191681 132 nt 0.4015
hsa_TMEM56_0000700 Intron-Exon chr1:95606229-95657237 chr1:95140673-95191681 165 nt 0.3879
hsa_TMEM56_0000800 Intron-Exon chr1:95606229-95658802 chr1:95140673-95193246 70 nt 0.4714
hsa_TMEM56_0000900 Exon-Exon chr1:95609447-95657235 chr1:95143891-95191679 181 nt 0.3425
hsa_TMEM56_0001000 Exon-Exon chr1:95609447-95657237 chr1:95143891-95191681 366 nt 0.4098
hsa_TMEM56_0001100 Exon-Exon chr1:95609447-95657289 chr1:95143891-95191733 181 nt 0.3425
Showing 151 to 160 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].