Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0003800 Exon-Exon chr1:95609447-95696550 chr1:95143891-95230994 577 nt 0.4142
hsa_RP11-57H12.6_0006500 Exon-Exon chr1:95616881-95616975 chr1:95151325-95151419 95 nt 0.3263
hsa_TMEM56_0001300 Exon-Exon chr1:95616881-95663161 chr1:95151325-95197605 250 nt 0.2520
hsa_TMEM56_0001800 Exon-Exon chr1:95657106-95663161 chr1:95191550-95197605 250 nt 0.2880
hsa_TMEM56_0001300 Exon-Exon chr1:95616881-95663161 chr1:95151325-95197605 250 nt 0.2520
hsa_TMEM56_0001800 Exon-Exon chr1:95657106-95663161 chr1:95191550-95197605 250 nt 0.2880
hsa_RP11-57H12.2_0000100 Intron-Intron chr1:95590555-95590754 chr1:95124999-95125198 200 nt 0.4450
hsa_RP11-57H12.2_0000200 Intron-Intron chr1:95598226-95598446 chr1:95132670-95132890 221 nt 0.3801
hsa_RP11-57H12.2_0000300 Intron-Intron chr1:95600338-95600531 chr1:95134782-95134975 194 nt 0.4278
hsa_RP11-57H12.2_0000400 Intron-Intron chr1:95600338-95602287 chr1:95134782-95136731 1950 nt 0.3959
Showing 11 to 20 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].