Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.3_0000900 Intron-Intron chr1:95658048-95658672 chr1:95192492-95193116 625 nt 0.3136
hsa_RP11-57H12.3_0001000 Intron-Intron chr1:95658048-95659951 chr1:95192492-95194395 1904 nt 0.3046
hsa_RP11-57H12.3_0001100 Intron-Intron chr1:95661502-95662255 chr1:95195946-95196699 754 nt 0.3501
hsa_RP11-57H12.3_0000400 Intron-Intron chr1:95639622-95645915 chr1:95174066-95180359 142 nt 0.4437
hsa_RP11-57H12.3_0000600 Intron-Intron chr1:95647469-95649102 chr1:95181913-95183546 1634 nt 0.3446
hsa_RP11-57H12.3_0000700 Intron-Intron chr1:95657417-95657556 chr1:95191861-95192000 140 nt 0.3214
hsa_RP11-57H12.3_0000800 Intron-Intron chr1:95657557-95657955 chr1:95192001-95192399 399 nt 0.4687
hsa_RP11-57H12.3_0000900 Intron-Intron chr1:95658048-95658672 chr1:95192492-95193116 625 nt 0.3136
hsa_RP11-57H12.3_0001000 Intron-Intron chr1:95658048-95659951 chr1:95192492-95194395 1904 nt 0.3046
hsa_RP11-57H12.3_0001100 Intron-Intron chr1:95661502-95662255 chr1:95195946-95196699 754 nt 0.3501
Showing 31 to 40 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].