Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0000100 Intron-Exon-Intron chr1:95586611-95639445 chr1:95121055-95173889 204 nt 0.4412
hsa_RP11-57H12.6_0000200 Intron-Exon-Intron chr1:95589850-95616975 chr1:95124294-95151419 71 nt 0.3803
hsa_RP11-57H12.6_0000300 Intron-Exon-Intron chr1:95589850-95618108 chr1:95124294-95152552 56 nt 0.3036
hsa_RP11-57H12.6_0000400 Intron-Exon-Intron chr1:95592846-95616975 chr1:95127290-95151419 160 nt 0.3875
hsa_RP11-57H12.6_0000500 Intron-Exon-Intron chr1:95600338-95618108 chr1:95134782-95152552 443 nt 0.3860
hsa_RP11-57H12.6_0000600 Intron-Exon-Intron chr1:95600507-95616975 chr1:95134951-95151419 345 nt 0.3739
hsa_RP11-57H12.6_0000700 Intron-Exon-Intron chr1:95602249-95616975 chr1:95136693-95151419 557 nt 0.4183
hsa_RP11-57H12.6_0000800 Intron-Exon-Intron chr1:95602249-95618136 chr1:95136693-95152580 84 nt 0.2976
hsa_RP11-57H12.6_0001200 Intron-Exon chr1:95603831-95609532 chr1:95138275-95143976 86 nt 0.3605
hsa_RP11-57H12.6_0001400 Intron-Exon-Intron chr1:95603831-95618158 chr1:95138275-95152602 106 nt 0.2925
Showing 41 to 50 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].