Basic Information

Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough TMEM56-RWDD3 Readthrough TMEM56-RWDD3 TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550 UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RP11-57H12.6_0000900 Intron-Exon-Intron chr1:95603831-95626705 chr1:95138275-95161149 250 nt 0.3880
hsa_RP11-57H12.6_0001600 Intron-Exon-Intron chr1:95603831-95644494 chr1:95138275-95178938 43 nt 0.5581
hsa_RP11-57H12.6_0001000 Intron-Exon-Intron chr1:95603831-95647030 chr1:95138275-95181474 250 nt 0.3160
hsa_RP11-57H12.6_0001900 Intron-Exon-Intron chr1:95603836-95616975 chr1:95138280-95151419 101 nt 0.3465
hsa_RP11-57H12.6_0002000 Intron-Exon-Intron chr1:95603836-95639445 chr1:95138280-95173889 169 nt 0.3964
hsa_RP11-57H12.6_0002100 Intron-Exon-Intron chr1:95606104-95616975 chr1:95140548-95151419 546 nt 0.3773
hsa_RP11-57H12.6_0002200 Intron-Exon-Intron chr1:95606104-95618158 chr1:95140548-95152602 292 nt 0.3664
hsa_RP11-57H12.6_0002300 Intron-Exon-Intron chr1:95606104-95639445 chr1:95140548-95173889 74 nt 0.4865
hsa_RP11-57H12.6_0002400 Intron-Exon-Intron chr1:95606183-95616975 chr1:95140627-95151419 154 nt 0.3831
hsa_RP11-57H12.6_0002500 Intron-Exon-Intron chr1:95606205-95616975 chr1:95140649-95151419 95 nt 0.3263
Showing 51 to 60 of 166 entries
Forensic Context

A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].