Basic Information
Symbol
circTMEM56
RNA Class
circRNA
Alias
TLCD4-RWDD3 Readthrough
TMEM56-RWDD3 Readthrough
TMEM56-RWDD3
TMEM56-RWDD3 Protein
Location (GRCh37)
1:95583013-95696550
UCSC Genome Browser
Location (GRCh38)
1:95117457-95230994
Host gene
TMEM56
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RP11-57H12.6_0005900 | Exon-Exon | chr1:95609502-95639445 | chr1:95143946-95173889 | 111 nt | 0.3514 |
| hsa_RP11-57H12.6_0006000 | Exon-Exon | chr1:95609518-95616975 | chr1:95143962-95151419 | 154 nt | 0.3831 |
| hsa_RP11-57H12.6_0006100 | Exon-Exon | chr1:95609538-95616975 | chr1:95143982-95151419 | 170 nt | 0.3412 |
| hsa_RP11-57H12.6_0006200 | Intron-Exon-Intron | chr1:95614258-95626705 | chr1:95148702-95161149 | 250 nt | 0.3560 |
| hsa_RP11-57H12.6_0006600 | Intron-Intron | chr1:95631643-95632211 | chr1:95166087-95166655 | 569 nt | 0.3937 |
| hsa_RP11-57H12.6_0006700 | Intron-Exon-Intron | chr1:95639372-95644494 | chr1:95173816-95178938 | 74 nt | 0.4865 |
| hsa_RP11-57H12.6_0000100 | Intron-Exon-Intron | chr1:95586611-95639445 | chr1:95121055-95173889 | 204 nt | 0.4412 |
| hsa_RP11-57H12.6_0000200 | Intron-Exon-Intron | chr1:95589850-95616975 | chr1:95124294-95151419 | 71 nt | 0.3803 |
| hsa_RP11-57H12.6_0000300 | Intron-Exon-Intron | chr1:95589850-95618108 | chr1:95124294-95152552 | 56 nt | 0.3036 |
| hsa_RP11-57H12.6_0000400 | Intron-Exon-Intron | chr1:95592846-95616975 | chr1:95127290-95151419 | 160 nt | 0.3875 |
Showing 81 to 90 of 166 entries
Forensic Context
A study in humans demonstrated that the circTMEM56 is significantly lower in the serum of patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls, showing a negative correlation with the severity of left ventricular obstruction in obstructive HCM and achieving an area under the curve (AUC) of 0.738 for diagnostic potential [Tian et al. DOI:10.3390/molecules26041155].