Basic Information
Symbol
circTPST1
RNA Class
circRNA
Alias
Tyrosylprotein Sulfotransferase 1
TANGO13A
Protein-Tyrosine Sulfotransferase 1
EC 2.8.2.20
TPST-1
Transport And Golgi Organization 13 Homolog A (Drosophila)
Transport And Golgi Organization 13 Homolog A
Location (GRCh37)
7:65705312-65751696
UCSC Genome Browser
Location (GRCh38)
7:66240325-66286709
Host gene
TPST1
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TPST1_0001700 | Exon-Exon | chr7:65705312-65751696 | chr7:66240325-66286709 | 1145 nt | 0.4445 |
Forensic Context
A study in humans demonstrated that circTPST1 is significantly decreased in the peripheral blood of Alzheimer's disease patients and may serve to distinguish this condition from other dementias [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary arteries from a postmortem case demonstrated that the circTPST1 was co-overexpressed in both left anterior descending and right coronary artery samples, identifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].