Basic Information
Symbol
circTTBK2
RNA Class
circRNA
Alias
Tau Tubulin Kinase 2
KIAA0847
Tau-Tubulin Kinase 2
SCA11
Spinocerebellar Ataxia 11
EC 2.7.11.1
EC 2.7.11
TTBK
Location (GRCh37)
15:43031947-43212808
UCSC Genome Browser
Location (GRCh38)
15:42739749-42920610
Host gene
TTBK2
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TTBK2_0000400 | Exon-Exon | chr15:43037968-43038455 | chr15:42745770-42746257 | 488 nt | 0.5512 |
| hsa_chr15_0115700 | Intergenic-Intergenic | chr15:43045315-43045429 | chr15:42753117-42753231 | 115 nt | 0.4870 |
| hsa_TTBK2_0002500 | Exon-Exon | chr15:43067333-43075833 | chr15:42775135-42783635 | 1018 nt | 0.4853 |
| hsa_TTBK2_0002600 | Exon-Exon | chr15:43067333-43103978 | chr15:42775135-42811780 | 1395 nt | 0.4738 |
| hsa_TTBK2_0002700 | Exon-Exon | chr15:43067333-43109295 | chr15:42775135-42817097 | 1461 nt | 0.4764 |
| hsa_TTBK2_0002800 | Exon-Exon | chr15:43067333-43122276 | chr15:42775135-42830078 | 1707 nt | 0.4769 |
| hsa_TTBK2_0002900 | Exon-Exon | chr15:43067333-43132631 | chr15:42775135-42840433 | 1781 nt | 0.4750 |
| hsa_TTBK2_0003000 | Exon-Exon | chr15:43067333-43170882 | chr15:42775135-42878684 | 2065 nt | 0.4717 |
| hsa_TTBK2_0004300 | Exon-Exon | chr15:43075617-43086999 | chr15:42783419-42794801 | 375 nt | 0.4667 |
| hsa_TTBK2_0004400 | Exon-Exon | chr15:43075617-43109295 | chr15:42783419-42817097 | 660 nt | 0.4576 |
Showing 1 to 10 of 190 entries
Forensic Context
A review consolidating findings from various studies indicates that in glioma models, the circTTBK2 targets miR-217 and the HNF1β/Derlin-1 pathway to prevent apoptosis and promote tumor cell proliferation, migration, and invasion [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].