Basic Information
Symbol
circTTBK2
RNA Class
circRNA
Alias
Tau Tubulin Kinase 2
KIAA0847
Tau-Tubulin Kinase 2
SCA11
Spinocerebellar Ataxia 11
EC 2.7.11.1
EC 2.7.11
TTBK
Location (GRCh37)
15:43031947-43212808
UCSC Genome Browser
Location (GRCh38)
15:42739749-42920610
Host gene
TTBK2
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TTBK2_0008000 | Exon-Exon | chr15:43102812-43132631 | chr15:42810614-42840433 | 605 nt | 0.4579 |
| hsa_TTBK2_0008100 | Exon-Exon | chr15:43102812-43164956 | chr15:42810614-42872758 | 753 nt | 0.4542 |
| hsa_TTBK2_0009000 | Exon-Exon | chr15:43103886-43109295 | chr15:42811688-42817097 | 159 nt | 0.4780 |
| hsa_TTBK2_0009100 | Exon-Exon | chr15:43103886-43120230 | chr15:42811688-42828032 | 264 nt | 0.4659 |
| hsa_TTBK2_0009200 | Exon-Exon | chr15:43103886-43122276 | chr15:42811688-42830078 | 405 nt | 0.4790 |
| hsa_TTBK2_0009300 | Exon-Exon | chr15:43103886-43132631 | chr15:42811688-42840433 | 479 nt | 0.4718 |
| hsa_TTBK2_0009700 | Exon-Exon | chr15:43109230-43109295 | chr15:42817032-42817097 | 66 nt | 0.5303 |
| hsa_TTBK2_0009800 | Exon-Exon | chr15:43109230-43122276 | chr15:42817032-42830078 | 312 nt | 0.4904 |
| hsa_TTBK2_0009900 | Exon-Exon | chr15:43109230-43132631 | chr15:42817032-42840433 | 386 nt | 0.4793 |
| hsa_TTBK2_0010000 | Exon-Exon | chr15:43109230-43164956 | chr15:42817032-42872758 | 534 nt | 0.4682 |
Showing 21 to 30 of 190 entries
Forensic Context
A review consolidating findings from various studies indicates that in glioma models, the circTTBK2 targets miR-217 and the HNF1β/Derlin-1 pathway to prevent apoptosis and promote tumor cell proliferation, migration, and invasion [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].