Basic Information
Symbol
circTTBK2
RNA Class
circRNA
Alias
Tau Tubulin Kinase 2
KIAA0847
Tau-Tubulin Kinase 2
SCA11
Spinocerebellar Ataxia 11
EC 2.7.11.1
EC 2.7.11
TTBK
Location (GRCh37)
15:43031947-43212808
UCSC Genome Browser
Location (GRCh38)
15:42739749-42920610
Host gene
TTBK2
Host category
mRNA
Forensic tag(s)
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TTBK2_0001800 | Exon-Exon | chr15:43044172-43045445 | chr15:42751974-42753247 | 1274 nt | 0.4403 |
| hsa_TTBK2_0001500 | Exon-Exon | chr15:43044172-43069440 | chr15:42751974-42777242 | 2075 nt | 0.4602 |
| hsa_TTBK2_0001600 | Exon-Exon | chr15:43044172-43075833 | chr15:42751974-42783635 | 2292 nt | 0.4603 |
| hsa_TTBK2_0001900 | Exon-Exon | chr15:43044172-43103978 | chr15:42751974-42811780 | 99 nt | 0.4545 |
| hsa_TTBK2_0002000 | Exon-Exon | chr15:43044172-43109295 | chr15:42751974-42817097 | 72 nt | 0.5417 |
| hsa_TTBK2_0002100 | Exon-Exon | chr15:43044172-43122276 | chr15:42751974-42830078 | 246 nt | 0.4797 |
| hsa_TTBK2_0002200 | Exon-Exon | chr15:43044172-43132631 | chr15:42751974-42840433 | 320 nt | 0.4688 |
| hsa_TTBK2_0001700 | Intron-Exon-Intron | chr15:43044172-43157993 | chr15:42751974-42865795 | 250 nt | 0.4200 |
| hsa_TTBK2_0002300 | Exon-Exon | chr15:43044172-43164956 | chr15:42751974-42872758 | 141 nt | 0.5035 |
| hsa_TTBK2_0002400 | Exon-Exon | chr15:43044172-43170882 | chr15:42751974-42878684 | 284 nt | 0.4507 |
Showing 61 to 70 of 190 entries
Forensic Context
A review consolidating findings from various studies indicates that in glioma models, the circTTBK2 targets miR-217 and the HNF1β/Derlin-1 pathway to prevent apoptosis and promote tumor cell proliferation, migration, and invasion [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746].