| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TUBD1_0004600 | Intron-Intron | chr17:57961067-57961361 | chr17:59883706-59884000 | 295 nt | 0.4542 |
| hsa_TUBD1_0004700 | Intron-Exon-Intron | chr17:57962022-57963591 | chr17:59884661-59886230 | 148 nt | 0.4527 |
| hsa_TUBD1_0004800 | Intron-Exon | chr17:57962022-57968289 | chr17:59884661-59890928 | 342 nt | 0.4795 |
| hsa_TUBD1_0004900 | Intron-Intron | chr17:57967466-57967608 | chr17:59890105-59890247 | 143 nt | 0.4196 |
| hsa_TUBD1_0005000 | Exon-Exon | chr17:57968192-57968402 | chr17:59890831-59891041 | 211 nt | 0.4218 |
A study in human hepatic stellate cells demonstrated that the circTUBD1 is upregulated after ionizing radiation exposure, and its silencing promotes miR-146a-5p, which targets TLR4 to increase apoptosis and decrease proinflammatory cytokines, thereby enhancing radiosensitivity [May et al. DOI:10.1016/j.trsl.2021.02.005].