Basic Information
Symbol
circXIST
RNA Class
circRNA
Alias
X Inactive Specific Transcript
NCRNA00001
LINC00001
DXS1089
Swd66
X Inactive Specific Transcript (Non-Protein Coding)
Long Intergenic Non-Protein Coding RNA 1
DXS399E
X (Inactive)-Specific Transcript (Non-Protein Coding)
X (Inactive)-Specific Transcript
NONHSAG054780.2
HSALNG0138602
SXI1
XIST
Location (GRCh37)
X:73045950-73051109
UCSC Genome Browser
Location (GRCh38)
X:73826115-73831274
Host gene
XIST
Host category
lncRNA
Forensic tag(s)
Sudden cardiac death diagnosis
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_XIST_0001900 | Exon-Exon | chrX:73045950-73051109 | chrX:73826115-73831274 | 2243 nt | 0.4391 |
Forensic Context
A study in humans demonstrated that the circXIST was identified among transcripts important for predicting multiple organ failure (MOF) outcome in a machine learning model analyzing blood transcriptomes from trauma patients [Duran et al. DOI:10.1186/s13613-024-01364-5]. A review of studies in humans, mice, and rats indicates the circXIST is differentially expressed in the peripheral blood of patients with coronary artery disease, demonstrating its potential as a biomarker for sudden cardiac death-related conditions [Tian et al. DOI:10.3390/molecules26041155].