Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0013900 Exon-Exon chr2:61719702-61720095 chr2:61492567-61492960 182 nt 0.3571
hsa_XPO1_0013700 Exon-Exon chr2:61719702-61727029 chr2:61492567-61499894 1158 nt 0.3636
hsa_XPO1_0013800 Exon-Exon chr2:61719702-61749818 chr2:61492567-61522683 1338 nt 0.3625
hsa_XPO1_0014000 Exon-Exon chr2:61719702-61753620 chr2:61492567-61526485 72 nt 0.3611
hsa_XPO1_0014200 Exon-Exon chr2:61720050-61727029 chr2:61492915-61499894 139 nt 0.3597
hsa_XPO1_0014300 Exon-Exon chr2:61720050-61729445 chr2:61492915-61502310 62 nt 0.3871
hsa_XPO1_0014400 Exon-Exon chr2:61720050-61749818 chr2:61492915-61522683 45 nt 0.2889
hsa_XPO1_0014500 Intron-Exon-Intron chr2:61720050-61752468 chr2:61492915-61525333 139 nt 0.3597
hsa_XPO1_0014100 Exon-Exon chr2:61720050-61761038 chr2:61492915-61533903 1390 nt 0.3683
hsa_XPO1_0014600 Intron-Intron chr2:61720189-61721028 chr2:61493054-61493893 840 nt 0.3750
Showing 181 to 190 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].