Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0020900 Exon-Exon chr2:61726891-61749777 chr2:61499756-61522642 216 nt 0.3657
hsa_XPO1_0021000 Intron-Exon-Intron chr2:61727637-61736245 chr2:61500502-61509110 250 nt 0.4080
hsa_XPO1_0021100 Intron-Exon-Intron chr2:61727637-61743659 chr2:61500502-61516524 250 nt 0.4240
hsa_XPO1_0021200 Intron-Exon-Intron chr2:61727681-61738340 chr2:61500546-61511205 250 nt 0.3400
hsa_XPO1_0021300 Intron-Exon-Intron chr2:61727857-61732372 chr2:61500722-61505237 250 nt 0.4160
hsa_XPO1_0021600 Exon-Exon chr2:61729131-61753656 chr2:61501996-61526521 282 nt 0.3617
hsa_XPO1_0021700 Exon-Exon chr2:61729131-61764803 chr2:61501996-61537668 521 nt 0.4184
hsa_XPO1_0022000 Exon-Exon chr2:61729384-61749818 chr2:61502249-61522683 135 nt 0.3778
hsa_XPO1_0022100 Exon-Exon chr2:61729384-61764722 chr2:61502249-61537587 185 nt 0.3946
hsa_XPO1_0022200 Intron-Intron chr2:61729845-61736223 chr2:61502710-61509088 250 nt 0.3400
Showing 231 to 240 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].