Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0026200 Intron-Exon chr2:61752405-61753597 chr2:61525270-61526462 107 nt 0.4486
hsa_XPO1_0026300 Intron-Exon chr2:61752405-61753637 chr2:61525270-61526502 147 nt 0.4422
hsa_XPO1_0026500 Intron-Exon chr2:61752627-61761038 chr2:61525492-61533903 200 nt 0.3650
hsa_XPO1_0026700 Exon-Exon chr2:61753555-61764803 chr2:61526420-61537668 341 nt 0.4516
hsa_chr2_0892600 Intergenic-Intergenic chr2:61754114-61760099 chr2:61526979-61532964 250 nt 0.3480
hsa_chr2_0892700 Intergenic-Intergenic chr2:61754161-61761546 chr2:61527026-61534411 250 nt 0.2600
hsa_XPO1_0026800 Intron-Intron chr2:61755339-61756546 chr2:61528204-61529411 1208 nt 0.3899
hsa_chr2_0892800 Intergenic-Intergenic chr2:61756183-61756561 chr2:61529048-61529426 379 nt 0.4327
hsa_chr2_0892900 Intergenic-Intergenic chr2:61756695-61757041 chr2:61529560-61529906 347 nt 0.4265
hsa_chr2_0893000 Intergenic-Intergenic chr2:61765029-61765339 chr2:61537894-61538204 311 nt 0.6592
Showing 281 to 290 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].