Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0006700 Exon-Exon chr2:61712903-61717911 chr2:61485768-61490776 621 nt 0.3816
hsa_XPO1_0006800 Exon-Exon chr2:61712903-61720188 chr2:61485768-61493053 1263 nt 0.3721
hsa_XPO1_0006900 Exon-Exon chr2:61712903-61724142 chr2:61485768-61497007 1749 nt 0.3716
hsa_XPO1_0007000 Exon-Exon chr2:61712903-61725927 chr2:61485768-61498792 1869 nt 0.3708
hsa_XPO1_0007100 Exon-Exon chr2:61712903-61726048 chr2:61485768-61498913 1918 nt 0.3702
hsa_XPO1_0007200 Exon-Exon chr2:61712903-61727029 chr2:61485768-61499894 2100 nt 0.3695
hsa_XPO1_0007300 Exon-Exon chr2:61712903-61729445 chr2:61485768-61502310 2207 nt 0.3684
hsa_XPO1_0007400 Intron-Exon-Intron chr2:61712903-61752468 chr2:61485768-61525333 250 nt 0.3200
hsa_XPO1_0007500 Exon-Exon chr2:61712903-61753656 chr2:61485768-61526521 2382 nt 0.3686
hsa_XPO1_0007600 Exon-Exon chr2:61712903-61761038 chr2:61485768-61533903 2514 nt 0.3707
Showing 31 to 40 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].