Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr11_0007700 | Intergenic-Intergenic | chr11:101984664-101985301 | chr11:102113933-102114570 | 638 nt | 0.3730 |
| hsa_YAP1_0001100 | Exon-Exon | chr11:101984875-102033302 | chr11:102114144-102162571 | 116 nt | 0.5517 |
| hsa_YAP1_0000900 | Intron-Exon-Intron | chr11:101984875-102035424 | chr11:102114144-102164693 | 2489 nt | 0.4070 |
| hsa_YAP1_0001200 | Exon-Exon | chr11:101984875-102076805 | chr11:102114144-102206074 | 182 nt | 0.5879 |
| hsa_YAP1_0001000 | Exon-Exon | chr11:101984875-102076817 | chr11:102114144-102206086 | 675 nt | 0.5393 |
| hsa_YAP1_0001300 | Exon-Exon | chr11:101984875-102080295 | chr11:102114144-102209564 | 48 nt | 0.4375 |
| hsa_YAP1_0001400 | Exon-Exon | chr11:101984875-102094483 | chr11:102114144-102223752 | 373 nt | 0.5389 |
| hsa_chr11_0007800 | Intergenic-Intergenic | chr11:101985056-102033544 | chr11:102114325-102162813 | 428 nt | 0.4322 |
| hsa_YAP1_0001500 | Intron-Intron | chr11:101987042-101988917 | chr11:102116311-102118186 | 1876 nt | 0.3380 |
| hsa_YAP1_0001600 | Intron-Intron | chr11:101990003-101990251 | chr11:102119272-102119520 | 249 nt | 0.3052 |
Showing 101 to 110 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].