Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr11_0009000 | Intergenic-Intergenic | chr11:102099726-102099886 | chr11:102228995-102229155 | 161 nt | 0.3851 |
| hsa_chr11_0009100 | Intergenic-Intergenic | chr11:102101719-102102029 | chr11:102230988-102231298 | 311 nt | 0.3891 |
| hsa_chr11_0009300 | Intergenic-Intergenic | chr11:102103040-102103276 | chr11:102232309-102232545 | 237 nt | 0.4008 |
| hsa_chr11_0009200 | Intergenic-Intergenic | chr11:102103040-102105376 | chr11:102232309-102234645 | 2337 nt | 0.3701 |
| hsa_chr11_0009400 | Intergenic-Intergenic | chr11:102103135-102103276 | chr11:102232404-102232545 | 142 nt | 0.4225 |
| hsa_chr11_0009500 | Intergenic-Intergenic | chr11:102103135-102103357 | chr11:102232404-102232626 | 223 nt | 0.4170 |
Showing 151 to 156 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].