Basic Information

Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator YAP65 YAP-1 Yes-Associated Protein YAP65 Homolog Transcriptional Coactivator YAP1 Yes Associated Protein 1 Protein Yorkie Homolog Yes-Associated Protein 1, 65kDa 65 KDa Yes-Associated Protein Yes-Associated Protein 2 Yes-Associated Protein 1 Yorkie Homolog COB1 YAP2 YAP YKI
Location (GRCh37)
11:101929611-102105376 UCSC Genome Browser
Location (GRCh38)
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_YAP1_0004400 Exon-Exon chr11:102076624-102076817 chr11:102205893-102206086 194 nt 0.5928
hsa_YAP1_0004500 Exon-Exon chr11:102076624-102080295 chr11:102205893-102209564 230 nt 0.5565
hsa_YAP1_0004600 Exon-Exon chr11:102076624-102094483 chr11:102205893-102223752 361 nt 0.5346
hsa_YAP1_0004700 Exon-Exon chr11:102076624-102098312 chr11:102205893-102227581 474 nt 0.5274
hsa_YAP1_0005800 Exon-Exon chr11:102094353-102098312 chr11:102223622-102227581 244 nt 0.5000
hsa_YAP1_0000100 Exon-Exon chr11:101981192-102104154 chr11:102110461-102233423 250 nt 0.3200
hsa_YAP1_0000700 Exon-Exon chr11:101984875-101985125 chr11:102114144-102114394 251 nt 0.5299
hsa_YAP1_0000800 Exon-Exon chr11:101984875-102104154 chr11:102114144-102233423 250 nt 0.3200
hsa_YAP1_0002300 Exon-Exon chr11:102033187-102056862 chr11:102162456-102186131 230 nt 0.5043
hsa_YAP1_0002400 Exon-Exon chr11:102033187-102076805 chr11:102162456-102206074 412 nt 0.5413
Showing 11 to 20 of 156 entries
Forensic Context

A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].