Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_YAP1_0002500 | Exon-Exon | chr11:102033187-102094483 | chr11:102162456-102223752 | 591 nt | 0.5228 |
| hsa_YAP1_0002600 | Exon-Exon | chr11:102033187-102104154 | chr11:102162456-102233423 | 250 nt | 0.3160 |
| hsa_YAP1_0003200 | Exon-Exon | chr11:102056749-102076805 | chr11:102186018-102206074 | 296 nt | 0.5372 |
| hsa_YAP1_0003300 | Exon-Exon | chr11:102056749-102080295 | chr11:102186018-102209564 | 344 nt | 0.5233 |
| hsa_YAP1_0004300 | Exon-Exon | chr11:102076624-102076805 | chr11:102205893-102206074 | 182 nt | 0.5879 |
| hsa_YAP1_0004400 | Exon-Exon | chr11:102076624-102076817 | chr11:102205893-102206086 | 194 nt | 0.5928 |
| hsa_YAP1_0004500 | Exon-Exon | chr11:102076624-102080295 | chr11:102205893-102209564 | 230 nt | 0.5565 |
| hsa_YAP1_0004600 | Exon-Exon | chr11:102076624-102094483 | chr11:102205893-102223752 | 361 nt | 0.5346 |
| hsa_YAP1_0004700 | Exon-Exon | chr11:102076624-102098312 | chr11:102205893-102227581 | 474 nt | 0.5274 |
| hsa_YAP1_0005800 | Exon-Exon | chr11:102094353-102098312 | chr11:102223622-102227581 | 244 nt | 0.5000 |
Showing 21 to 30 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].