Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_C11orf70_0000500 | Exon-Intergenic | chr11:101929611-102056868 | chr11:102058880-102186137 | 250 nt | 0.3000 |
| hsa_C11orf70_0000500 | Exon-Intergenic | chr11:101929611-102056868 | chr11:102058880-102186137 | 250 nt | 0.3000 |
| hsa_RP11-864G5.3_0000100 | Exon-Intergenic | chr11:102101600-102102270 | chr11:102230869-102231539 | 671 nt | 0.3458 |
| hsa_RP11-864G5.3_0000100 | Exon-Intergenic | chr11:102101600-102102270 | chr11:102230869-102231539 | 671 nt | 0.3458 |
| hsa_YAP1_0000200 | Exon-Exon | chr11:101981329-101984919 | chr11:102110598-102114188 | 45 nt | 0.6000 |
| hsa_YAP1_0000500 | Exon-Exon | chr11:101983331-102033302 | chr11:102112600-102162571 | 146 nt | 0.4110 |
| hsa_YAP1_0000600 | Exon-Intron | chr11:101983331-102035424 | chr11:102112600-102164693 | 146 nt | 0.4110 |
| hsa_YAP1_0000300 | Exon-Exon | chr11:101983331-102080295 | chr11:102112600-102209564 | 857 nt | 0.5099 |
| hsa_YAP1_0000400 | Exon-Exon | chr11:101983331-102098312 | chr11:102112600-102227581 | 1101 nt | 0.5077 |
| hsa_chr11_0007700 | Intergenic-Intergenic | chr11:101984664-101985301 | chr11:102113933-102114570 | 638 nt | 0.3730 |
Showing 31 to 40 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].