Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_YAP1_0002800 | Exon-Exon | chr11:102033187-102080295 | chr11:102162456-102209564 | 122 nt | 0.5492 |
| hsa_YAP1_0002900 | Exon-Exon | chr11:102033215-102076817 | chr11:102162484-102206086 | 396 nt | 0.5505 |
| hsa_YAP1_0003000 | Intron-Intron | chr11:102044369-102046462 | chr11:102173638-102175731 | 2094 nt | 0.4126 |
| hsa_chr11_0008300 | Intergenic-Intergenic | chr11:102045835-102046335 | chr11:102175104-102175604 | 501 nt | 0.4291 |
| hsa_YAP1_0003100 | Intron-Exon | chr11:102049534-102056862 | chr11:102178803-102186131 | 250 nt | 0.3840 |
| hsa_YAP1_0003400 | Exon-Exon | chr11:102056749-102076817 | chr11:102186018-102206086 | 314 nt | 0.5382 |
| hsa_YAP1_0003500 | Exon-Exon | chr11:102056749-102094483 | chr11:102186018-102223752 | 293 nt | 0.4710 |
| hsa_chr11_0008400 | Intergenic-Intergenic | chr11:102061188-102071289 | chr11:102190457-102200558 | 250 nt | 0.3960 |
| hsa_chr11_0008500 | Intergenic-Intergenic | chr11:102062813-102063039 | chr11:102192082-102192308 | 227 nt | 0.3480 |
| hsa_YAP1_0003600 | Intron-Exon | chr11:102063556-102076805 | chr11:102192825-102206074 | 250 nt | 0.3880 |
Showing 61 to 70 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].