Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_YAP1_0003700 | Intron-Exon-Intron | chr11:102063556-102080295 | chr11:102192825-102209564 | 314 nt | 0.5191 |
| hsa_YAP1_0003800 | Intron-Exon-Intron | chr11:102071195-102080295 | chr11:102200464-102209564 | 250 nt | 0.4160 |
| hsa_YAP1_0003900 | Intron-Exon | chr11:102072912-102076805 | chr11:102202181-102206074 | 250 nt | 0.4680 |
| hsa_YAP1_0004000 | Intron-Exon | chr11:102072936-102076805 | chr11:102202205-102206074 | 93 nt | 0.6129 |
| hsa_chr11_0008600 | Intergenic-Intergenic | chr11:102073204-102077290 | chr11:102202473-102206559 | 250 nt | 0.2880 |
| hsa_YAP1_0004100 | Intron-Exon | chr11:102074719-102076805 | chr11:102203988-102206074 | 317 nt | 0.5268 |
| hsa_YAP1_0004200 | Intron-Exon-Intron | chr11:102074719-102076817 | chr11:102203988-102206086 | 239 nt | 0.5607 |
| hsa_YAP1_0004900 | Intron-Exon-Intron | chr11:102076624-102077722 | chr11:102205893-102206991 | 1099 nt | 0.4440 |
| hsa_YAP1_0005000 | Exon-Exon | chr11:102076635-102076805 | chr11:102205904-102206074 | 171 nt | 0.5906 |
| hsa_YAP1_0005100 | Exon-Exon | chr11:102076647-102094483 | chr11:102205916-102223752 | 131 nt | 0.4962 |
Showing 71 to 80 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].