Basic Information
Symbol
circYAP1
RNA Class
circRNA
Alias
Yes1 Associated Transcriptional Regulator
YAP65
YAP-1
Yes-Associated Protein YAP65 Homolog
Transcriptional Coactivator YAP1
Yes Associated Protein 1
Protein Yorkie Homolog
Yes-Associated Protein 1, 65kDa
65 KDa Yes-Associated Protein
Yes-Associated Protein 2
Yes-Associated Protein 1
Yorkie Homolog
COB1
YAP2
YAP
YKI
Location (GRCh37)
11:101929611-102105376
UCSC Genome Browser
Location (GRCh38)
11:102058880-102234645
Host gene
YAP1
Host category
mRNA
Forensic tag(s)
Cause of death analysis
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_YAP1_0005200 | Intron-Exon-Intron | chr11:102077660-102080295 | chr11:102206929-102209564 | 2636 nt | 0.3596 |
| hsa_YAP1_0005300 | Intron-Exon-Intron | chr11:102079971-102080295 | chr11:102209240-102209564 | 325 nt | 0.3938 |
| hsa_YAP1_0005400 | Exon-Exon | chr11:102080248-102098312 | chr11:102209517-102227581 | 48 nt | 0.4375 |
| hsa_YAP1_0005500 | Intron-Intron | chr11:102088391-102088768 | chr11:102217660-102218037 | 378 nt | 0.5026 |
| hsa_YAP1_0005600 | Intron-Exon-Intron | chr11:102091164-102094483 | chr11:102220433-102223752 | 242 nt | 0.4380 |
| hsa_YAP1_0005700 | Intron-Intron | chr11:102093235-102093394 | chr11:102222504-102222663 | 160 nt | 0.4500 |
| hsa_YAP1_0006000 | Intron-Intron | chr11:102095175-102095432 | chr11:102224444-102224701 | 258 nt | 0.3101 |
| hsa_chr11_0008800 | Intergenic-Intergenic | chr11:102096244-102096391 | chr11:102225513-102225660 | 148 nt | 0.3649 |
| hsa_chr11_0008900 | Intergenic-Intergenic | chr11:102098773-102099001 | chr11:102228042-102228270 | 229 nt | 0.3100 |
| hsa_chr11_0009000 | Intergenic-Intergenic | chr11:102099726-102099886 | chr11:102228995-102229155 | 161 nt | 0.3851 |
Showing 81 to 90 of 156 entries
Forensic Context
A study in human neonates with asphyxia-induced acute kidney injury identified 296 differentially expressed circular RNAs, with hsa_circ_0008898 and hsa_circ_0005519 significantly upregulated and hsa_circ_0132279, hsa_circ_0112327, and hsa_circ_0017647 significantly downregulated in peripheral blood, as validated by qPCR [Pan et al. DOI:10.1002/kjm2.12644]. The literature notes that the circYAP1 enhances the interaction between tropomyosin-4 and γ-actin to decrease actin polymerization, causing cardiac fibrosis, and also forms a complex to block YAP protein translation [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].