Basic Information
Symbol
circYES1
RNA Class
circRNA
Alias
YES Proto-Oncogene 1, Src Family Tyrosine Kinase
HsT441
C-Yes
Yes
V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1
Tyrosine-Protein Kinase Yes
Proto-Oncogene C-Yes
EC 2.7.10.2
YES1 Proto-Oncogene, Src Family Tyrosine Kinase
Proto-Oncogene Tyrosine-Protein Kinase YES
Yamaguchi Sarcoma Oncogene
Cellular Yes-1 Protein
EC 2.7.10
P61-YES
P61-Yes
YES
Location (GRCh37)
18:745708-751804
UCSC Genome Browser
Location (GRCh38)
18:745708-751804
Host gene
YES1
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_YES1_0003400 | Exon-Exon | chr18:745708-751804 | chr18:745708-751804 | 453 nt | 0.3775 |
Forensic Context
A review consolidating research in humans and rodent models indicates that the circYES1 is upregulated in glioma tissues and promotes tumor cell proliferation and invasion by sequestering miR-143-3p to derepress ITGB8 [Mehta et al. DOI:10.1016/j.pneurobio.2020.101746][Lee et al. DOI:10.1016/j.biopha.2018.12.052].