Basic Information

Symbol
circBIRC6
RNA Class
circRNA
Alias
Baculoviral IAP Repeat Containing 6 BRUCE Dual E2 Ubiquitin-Conjugating Enzyme/E3 Ubiquitin-Protein Ligase BIRC6 BIR Repeat-Containing Ubiquitin-Conjugating Enzyme Baculoviral IAP Repeat-Containing Protein 6 Apollon Ubiquitin-Conjugating BIR-Domain Enzyme Apollon Ubiquitin-Conjugating BIR Domain Enzyme Apollon RING-Type E3 Ubiquitin Transferase BIRC6 Baculoviral IAP Repeat-Containing 6 EC 2.3.2.24 KIAA1289 APOLLON
Location (GRCh37)
2:32472404-32843965 UCSC Genome Browser
Location (GRCh38)
2:32247335-32618898
UCSC Genome Browser Search in Marker Scope
Host gene
BIRC6
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_BIRC6_0017500 Exon-Exon chr2:32626231-32738221 chr2:32401163-32513154 250 nt 0.3760
hsa_BIRC6_0018600 Exon-Exon chr2:32626231-32819127 chr2:32401163-32594060 152 nt 0.4276
hsa_BIRC6_0017600 Exon-Exon chr2:32626231-32824967 chr2:32401163-32599900 250 nt 0.3640
hsa_BIRC6_0019500 Exon-Exon chr2:32626531-32641231 chr2:32401463-32416163 1615 nt 0.4093
hsa_BIRC6_0019400 Exon-Exon chr2:32626531-32670736 chr2:32401463-32445668 250 nt 0.3520
hsa_BIRC6_0019600 Intron-Intron chr2:32628258-32628702 chr2:32403190-32403634 445 nt 0.2787
hsa_BIRC6_0019700 Intron-Intron chr2:32629941-32631228 chr2:32404873-32406160 1288 nt 0.3548
hsa_BIRC6_0019800 Intron-Intron chr2:32629970-32630177 chr2:32404902-32405109 208 nt 0.3654
hsa_BIRC6_0020900 Intron-Exon-Intron chr2:32631567-32633457 chr2:32406499-32408389 1891 nt 0.3733
hsa_BIRC6_0021100 Intron-Exon-Intron chr2:32631567-32642990 chr2:32406499-32417922 59 nt 0.4237
Showing 1091 to 1100 of 2270 entries
Forensic Context

A study in human embryonic stem cells demonstrated that the circBIRC6 controls pluripotency by sequestering miR-34 and miR-145 [Patop et al. DOI:10.15252/embj.2018100836], and it acts as a sponge for miR-34a and miR-145 to relieve the suppression of NANOG, OCT4, and SOX2 expression [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans demonstrated that the BIRC6 gene can generate hundreds of circRNA isoforms, and their expression changes during tumorigenesis can differ [Li et al. DOI:10.1093/bib/bby006].