Basic Information

Symbol
circBIRC6
RNA Class
circRNA
Alias
Baculoviral IAP Repeat Containing 6 BRUCE Dual E2 Ubiquitin-Conjugating Enzyme/E3 Ubiquitin-Protein Ligase BIRC6 BIR Repeat-Containing Ubiquitin-Conjugating Enzyme Baculoviral IAP Repeat-Containing Protein 6 Apollon Ubiquitin-Conjugating BIR-Domain Enzyme Apollon Ubiquitin-Conjugating BIR Domain Enzyme Apollon RING-Type E3 Ubiquitin Transferase BIRC6 Baculoviral IAP Repeat-Containing 6 EC 2.3.2.24 KIAA1289 APOLLON
Location (GRCh37)
2:32472404-32843965 UCSC Genome Browser
Location (GRCh38)
2:32247335-32618898
UCSC Genome Browser Search in Marker Scope
Host gene
BIRC6
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_BIRC6_0096200 Exon-Exon chr2:32743321-32774548 chr2:32518254-32549481 169 nt 0.4675
hsa_BIRC6_0096000 Exon-Exon chr2:32743321-32836649 chr2:32518254-32611582 250 nt 0.3600
hsa_BIRC6_0096300 Exon-Exon chr2:32743342-32750695 chr2:32518275-32525628 550 nt 0.4127
hsa_BIRC6_0096400 Exon-Exon chr2:32743414-32756618 chr2:32518347-32531551 849 nt 0.4205
hsa_BIRC6_0096500 Exon-Exon chr2:32743414-32773081 chr2:32518347-32548014 1533 nt 0.4442
hsa_BIRC6_0096700 Exon-Exon chr2:32743884-32770927 chr2:32518817-32545860 1317 nt 0.4404
hsa_BIRC6_0096800 Exon-Exon chr2:32743945-32750695 chr2:32518878-32525628 165 nt 0.4848
hsa_BIRC6_0096900 Intron-Intron chr2:32744200-32744379 chr2:32519133-32519312 180 nt 0.3278
hsa_BIRC6_0097000 Intron-Intron chr2:32745186-32745332 chr2:32520119-32520265 147 nt 0.3197
hsa_chr2_0734700 Intergenic-Intergenic chr2:32746507-32746777 chr2:32521440-32521710 271 nt 0.4502
Showing 1511 to 1520 of 2270 entries
Forensic Context

A study in human embryonic stem cells demonstrated that the circBIRC6 controls pluripotency by sequestering miR-34 and miR-145 [Patop et al. DOI:10.15252/embj.2018100836], and it acts as a sponge for miR-34a and miR-145 to relieve the suppression of NANOG, OCT4, and SOX2 expression [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans demonstrated that the BIRC6 gene can generate hundreds of circRNA isoforms, and their expression changes during tumorigenesis can differ [Li et al. DOI:10.1093/bib/bby006].