Basic Information

Symbol
circBIRC6
RNA Class
circRNA
Alias
Baculoviral IAP Repeat Containing 6 BRUCE Dual E2 Ubiquitin-Conjugating Enzyme/E3 Ubiquitin-Protein Ligase BIRC6 BIR Repeat-Containing Ubiquitin-Conjugating Enzyme Baculoviral IAP Repeat-Containing Protein 6 Apollon Ubiquitin-Conjugating BIR-Domain Enzyme Apollon Ubiquitin-Conjugating BIR Domain Enzyme Apollon RING-Type E3 Ubiquitin Transferase BIRC6 Baculoviral IAP Repeat-Containing 6 EC 2.3.2.24 KIAA1289 APOLLON
Location (GRCh37)
2:32472404-32843965 UCSC Genome Browser
Location (GRCh38)
Host gene
BIRC6
Host category
mRNA
Forensic tag(s)
Other applications
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_BIRC6_0012200 Exon-Exon chr2:32613818-32716625 chr2:32388750-32491558 250 nt 0.3120
hsa_BIRC6_0012300 Exon-Exon chr2:32613818-32718734 chr2:32388750-32493667 250 nt 0.2840
hsa_BIRC6_0012400 Exon-Exon chr2:32613818-32735061 chr2:32388750-32509994 250 nt 0.3360
hsa_BIRC6_0012500 Exon-Exon chr2:32613818-32820211 chr2:32388750-32595144 250 nt 0.3040
hsa_BIRC6_0012600 Exon-Exon chr2:32613818-32843965 chr2:32388750-32618898 250 nt 0.2960
hsa_BIRC6_0013600 Exon-Exon chr2:32617107-32620661 chr2:32392039-32395593 195 nt 0.4615
hsa_BIRC6_0013700 Exon-Exon chr2:32617107-32626453 chr2:32392039-32401385 418 nt 0.4617
hsa_BIRC6_0013800 Exon-Exon chr2:32617107-32626691 chr2:32392039-32401623 579 nt 0.4525
hsa_BIRC6_0013900 Exon-Exon chr2:32617107-32631625 chr2:32392039-32406557 638 nt 0.4498
hsa_BIRC6_0014000 Exon-Exon chr2:32617107-32641231 chr2:32392039-32416163 2033 nt 0.4201
Showing 71 to 80 of 2270 entries
Forensic Context

A study in human embryonic stem cells demonstrated that the circBIRC6 controls pluripotency by sequestering miR-34 and miR-145 [Patop et al. DOI:10.15252/embj.2018100836], and it acts as a sponge for miR-34a and miR-145 to relieve the suppression of NANOG, OCT4, and SOX2 expression [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A study in humans demonstrated that the BIRC6 gene can generate hundreds of circRNA isoforms, and their expression changes during tumorigenesis can differ [Li et al. DOI:10.1093/bib/bby006].